Mar 3, 2020
Analysis of the PPMI dataset has shown that compared to people with sporadic forms of Parkinson’s, newly diagnosed people carrying GBA mutations are less severely impaired, and those with LRRK2 mutations appear more mildly affected.
Jan 14, 2020
Ambroxol was found to be safe and well tolerated in an open label trial in 18 people with Parkinson’s. It enters the brain and appears to increase levels of its chemical target GCase.
Nov 27, 2019
New research into the cellular clearance pathways governed by the GBA gene has shown reduced activity associated with both ageing and idiopathic Parkinson’s.
Apr 7, 2019
Using the largest ever genetics dataset
Nov 8, 2018
Insights into pathways in mitochondria and oxidative stress