Mar 3, 2020
Analysis of the PPMI dataset has shown that compared to people with sporadic forms of Parkinson’s, newly diagnosed people carrying GBA mutations are less severely impaired, and those with LRRK2 mutations appear more mildly affected.
Oct 13, 2019
A new preclinical study has shown that LRRK2 inhibition in an animal model of Parkinson’s can improve lysosomal health and reduce alpha synuclein accumulation in dopaminergic neurons.
Jul 19, 2019
Largest UK population based study of PD found up to 10% of affected individuals carry a pathogenic mutation
Nov 8, 2018
Insights into pathways in mitochondria and oxidative stress